Pathophysiology, Investigations, and Treatment in Patients with Hydatidiform Mole
Omar Elsaka *
Mansoura Manchester Medical Program (MMMP), Department of Gynecology and Obstetrics, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Moneer Ayman Noureldean
Mansoura Manchester Medical Program (MMMP), Department of Gynecology and Obstetrics, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Mohamed Adel Gamil
Mansoura Manchester Medical Program (MMMP), Department of Gynecology and Obstetrics, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Mostafa Tarek Ghazali
Mansoura Manchester Medical Program (MMMP), Department of Gynecology and Obstetrics, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Ashraf Hamada Abd Al-Razik
Mansoura Manchester Medical Program (MMMP), Department of Gynecology and Obstetrics, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Dalia Hisham
Mansoura Manchester Medical Program (MMMP), Department of Gynecology and Obstetrics, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
*Author to whom correspondence should be addressed.
Abstract
Background: A hydatiform mole (sometimes called a molar pregnancy) is a type of Gestational Trophoblastic Disease (GTD) that starts in the placenta and can spread. The tumor arises from prenatal tissue rather than maternal tissue, which makes it distinctive. Hydatiform moles (HM) are divided into two types: total and partial. They are the noninvasive form of gestational trophoblastic illness. While hydatiform moles are usually considered benign, they are premalignant and can develop into malignant and invasive moles. This activity discusses the pathophysiology, examination, and treatment of hydatiform moles, as well as the role of the interprofessional team in inpatient care.
Conclusion: The goal of this review article is to identify the etiology of a hydatiform mole, describe the presentation of a patient with a hydatiform mole, review the treatment and management options for hydatiform moles, and explain interprofessional team strategies for improving care coordination and communication to advance the treatment of hydatiform moles and improve outcomes.
Keywords: Choriocarcinoma, fertilization, hydatidiform mole, invasive mole, trophoblast